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Prospective comparison of acupuncture with sham acupuncture to determine impact on sedation and analgesia in mechanically ventilated critically ill patients

Effect of acupuncture on sedation and analgesia in mechanically ventilated critically ill patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052650
Enrollment
Unknown
Registered
2021-11-03
Start date
2021-11-03
Completion date
Unknown
Last updated
2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mechanically ventilation

Interventions

Experimental group1:Deep acupuncture treatment with acupuncture manipulation combined with alternating frequency electrical stimulation
Experimental group2:No needling technique, superficial needling beside acupoints with low frequency electrical stimulation
Control group:None

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years; 2. Estimated required mechanical ventilation > 24 hours; 3. Continuous intravenous administration of sedative and analgesic medications; 4. Willingness to provide informed consent prior to enrollment; 5. Be able to comply with all follow-up evaluations (in investigator's opinion).

Exclusion criteria

Exclusion criteria: 1. There is skin damage near the acupoint; 2. Coagulation disorders (bleeding time > 4 minutes, platelets < 50,000/µ); 3. Nervous system diseases (previous stroke, cerebral palsy) that are easy to confuse the diagnosis, active epilepsy; 4. Severe dementia or mental disorder; 5. Liver dysfunction with Childs-Pugh grade B or C; 6. Second or third degree atrioventricular block; 7. Alcoholism, drug abuse or benzodiazepine dependence; 8. The patient is in a dying state, and life support is planned to be discontinued; 9. Pregnancy or breastfeeding; 10. Currently participating in any other investigational therapy or device trial.

Design outcomes

Primary

MeasureTime frame
duration of mechanical ventilation;

Secondary

MeasureTime frame
Doses of sedatives and analgesics throughout the study;the duration of intensive care unit length of stay;hospital length of stay;the number of ventilator-free days at 28 days;

Countries

China

Contacts

Public ContactZhang Minzhou

Guangdong Provincial Hospital of Traditional Chinese Medicine

minzhouzhang@gzucm.edu.cn+86 13924266368

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026