chalazion
Conditions
Interventions
Normal control group:None
Sponsors
Xiamen Eye Center affiliated to Xiamen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Palpable hard mass under the eyelid, connected to the tarsal plate without red pain, skin uplift on the surface, no adhesion with the mass, conjunctiva purplish red or grayish red facing the conjunctival surface of the mass; 2. Regardless of gender; 3. The specimen of the subject who underwent surgical resection was confirmed to be a meibomian gland cyst by pathological examination; 4. Signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Study eye infection, including secondary infection of meibomian gland cyst, blepharitis, eyelid skin infection, orbital cellulitis and viral, bacterial, mycobacterial, protozoan or fungal infection of cornea, conjunctiva, lacrimal gland, lacrimal duct, lacrimal sac; 2. Duration of disease < 2 weeks; 3. Unpalpable chalazion; 4. Suspected malignant tumor; 5. Study eyes have undergone eye surgery, including intraocular, eyelid, eye plastic surgery, lacrimal punctum embolism, lacrimal canaliculoplasty, conjunctival, corneal or refractive surgery; 6. Study eyes have trauma; 7. Study eyes have the following eyelid abnormalities, including ectropion, ectropion, tumor, blepharospasm, insufficiency, non-chalazion secondary ptosis; 8. Study eyes complicated with glaucoma; 9. Study eyes have allergies, such as seasonal conjunctivitis and giant papillary conjunctivitis; 10. Study eyes have a history of inflammation or endophthalmitis within 180 days before sampling, including keratitis, scleral exosclerositis, scleritis, uveitis, retinal inflammation; 11. Study eyes with abnormal corneal integrity; 12. Study eyes wear corneal contact lenses; 13. Use eye drops (artificial tears, antibiotics, steroids, cyclosporine and non-steroidal anti-inflammatory drugs) within 180 days before sampling; 14. Oral drugs (antibiotics, steroids and non-steroidal anti-inflammatory drugs) within 180 days before eye sampling; 15. Complicated with systemic diseases (diabetes, hyperthyroidism, stevens-Johnsonsyndrome, vitamin A deficiency, rheumatoid arthritis, Wegener's granulomatosis, sarcoidosis, leukemia, systemic lupus erythematosus, Sjogren's syndrome); 16. Pregnant and lactating women, or women who are fertile and do not use appropriate contraceptives are judged according to the subjects' self-reports; 17. Subjects participate in other ophthalmic clinical trials involving therapeutic drugs or medical devices within 180 days before sampling.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abundance and type of flora;Tear component; | — |
Countries
China
Contacts
Public ContactWu Huping
Xiamen Eye Center affiliated to Xiamen University
Outcome results
None listed