post ischemic stroke cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.The first onset of ischemic stroke and it meets the WHO diagnostic criteria for stroke and the Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke in China 2014 issued in 2015, confirmed by CT or MRI imaging scans of the head; 2.Course of disease >= 1 Months and <= 12 months; 3.Stable condition after ischemic stroke, with stable vital signs; 4.Aged 18 to 85 years; 5.No related cognitive impairment related medical history and symptoms before stroke; 6.Specialist evaluation suggests normal/Mild to moderate cognitive impairment; 7.Voluntary participation, the patient himself or his immediate family will sign an informed consent form and complete the CRF form.
Exclusion criteria
Exclusion criteria: 1. Cognitive impairment caused by other dementias, such as lewy body dementia and Pick disease; 2. Unstable vital signs and complicated with severe chronic diseases; 3. Intracranial implantation of metal and electronic equipment; Skull defects and metal skull repair operation; 4. Use with caution in patients with bleeding tendency (e.g., acute stage of cerebral hemorrhage, coagulation disorder, etc.); 5. Patients with implanted electronic devices are prohibited (e.g., pacemaker carriers); 6. Pregnant women. 7. Are participating in another clinical trial; 8. The investigator believes that there are any conditions that may harm the subject or cause the subject to fail to meet or perform the research requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Verbal Fluency Test;Working Memory, WM;Go/No-Go task test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale (MOCA);mini-Mental Status examination;clinical dementia rating;Event related potential P300; | — |
Countries
China
Contacts
The Second Affiliated Hosptail of Xi'an Jiaotong University