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Clinical study on the treatment of cognitive Impairment after ischemic stroke by transcranial direct current stimulation (tDCS) based on near-infrared imaging of brain function: a randomized parallel controlled trial

Clinical study on the treatment of cognitive Impairment after ischemic stroke by transcranial direct current stimulation (tDCS) based on near-infrared imaging of brain function: a randomized parallel controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052623
Enrollment
Unknown
Registered
2021-11-02
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post ischemic stroke cognitive impairment

Interventions

Experimental group:Transcranial direct current stimulation+Routine rehabilitation program

Sponsors

The Second Affiliated Hosptail of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.The first onset of ischemic stroke and it meets the WHO diagnostic criteria for stroke and the Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke in China 2014 issued in 2015, confirmed by CT or MRI imaging scans of the head; 2.Course of disease >= 1 Months and <= 12 months; 3.Stable condition after ischemic stroke, with stable vital signs; 4.Aged 18 to 85 years; 5.No related cognitive impairment related medical history and symptoms before stroke; 6.Specialist evaluation suggests normal/Mild to moderate cognitive impairment; 7.Voluntary participation, the patient himself or his immediate family will sign an informed consent form and complete the CRF form.

Exclusion criteria

Exclusion criteria: 1. Cognitive impairment caused by other dementias, such as lewy body dementia and Pick disease; 2. Unstable vital signs and complicated with severe chronic diseases; 3. Intracranial implantation of metal and electronic equipment; Skull defects and metal skull repair operation; 4. Use with caution in patients with bleeding tendency (e.g., acute stage of cerebral hemorrhage, coagulation disorder, etc.); 5. Patients with implanted electronic devices are prohibited (e.g., pacemaker carriers); 6. Pregnant women. 7. Are participating in another clinical trial; 8. The investigator believes that there are any conditions that may harm the subject or cause the subject to fail to meet or perform the research requirements.

Design outcomes

Primary

MeasureTime frame
Verbal Fluency Test;Working Memory, WM;Go/No-Go task test;

Secondary

MeasureTime frame
Montreal Cognitive Assessment Scale (MOCA);mini-Mental Status examination;clinical dementia rating;Event related potential P300;

Countries

China

Contacts

Public ContactZhang Qiaojun

The Second Affiliated Hosptail of Xi'an Jiaotong University

zhangqj@mail.xjtu.cn+86 13891867155

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026