non-coronary obstructive ischemic heart disease
Conditions
Interventions
Experimental group:Take Tongxinluo capsule
Control group:Nicodil was taken orally
Sponsors
Huadong Hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years, No gender limitation; 2. Diagnostic criteria for stable angina: there was no change in the frequency, duration, cause or relief mode of angina attacks within the last 60 days;There was no evidence of recent myocardial injury; 3. CAG shows non-obstructive coronary arteries, including normal coronary arteries (stenosis < 30%) and mild stenosis (30% < Narrow < 50%); 4.CSF diagnostic criteria: correct TIMI frame Count (CTFC), that is, coronary blood flow from vessel opening to vessel terminal exceeds 27 frames when the angiographic image acquisition speed is 30 frames /s; 5. Evidence of myocardial ischemia: there is objective evidence of myocardial ischemia on ecg or radionuclide myocardial perfusion imaging in resting or exercise state.
Exclusion criteria
Exclusion criteria: 1. Severe aortic stenosis, hypertrophic obstructive cardiomyopathy, congestive heart failure, and malignant tumors; 2. Patients with a clear history of MI, PCI and CABG 6 months prior to screening; 3. Use of glucocorticoids within 3 months before screening; 4. Renal function impairment (serum creatinine >= 140µmol/L) or liver function impairment (ALT and/or AST >= 100IU/L).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of angina pectoris; | — |
Secondary
| Measure | Time frame |
|---|---|
| Myocardial injury index (TnT, TnI, CK-MB); | — |
Countries
China
Contacts
Public ContactHong Weilin
Huadong Hospital affiliated to Fudan University
Outcome results
None listed