Colorectal disease
Conditions
Interventions
Group A:0.2mg/kg Remimazolam was used as the induction dose
Group C:2mg/kg Propofol was used as the induction dose
Group B:0.25mg/kg Remimazolam was used as the induction dose
Sponsors
Hangzhou First People's Hospital affiliated to Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. ASA class I or II; 2. BMI 18-28kg/m2; 3. Aged 18 to 65 years; 4. Patients receiving routine colonoscopy diagnosis and treatment.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women and patients (including men) with birth plans within 3 months; 2.Patients with obvious respiratory and circulatory dysfunction, abnormal blood routine and biochemical indexes before surgery; 3.Persons suffering from severe neuropsychiatric disorders; 4.Take benzodiazepines or opioids every day for 1 month or intermittenously for the last 3 months; 5.Allergic or contraindicated to benzodiazepines, opioids, propofol, flumazenil, naloxone and other drugs and their components; 6.Patients assessed as having difficulty in respiratory management: modified Martensite score III or above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved alertness/sedation score;Body dynamic response;awakening time;Reach the standard departure time; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;oxygen saturation;heart rate;respiratory rate; | — |
Countries
China
Contacts
Public ContactSun Qirui
Hangzhou First People's Hospital affiliated to Zhejiang University
Outcome results
None listed