Patient with hysteroscopic procedure
Conditions
Interventions
E1 group:esketamine:0.2mg/kg combine with propofol:2.5mg/kg
E2 group:esketamine:0.3mg/kg combine with propofol:2.5mg/kg
E3 group:esketamine:0.4mg/kg combine with propofol:2.5mg/kg
F group:sufentanil:0.4mg/kg combine with propofol:2.5mg/kg
Sponsors
Hengyang Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 45 years, BMI 18-30 kg/m2; 2. ASA I-II.
Exclusion criteria
Exclusion criteria: 1. Hypertension, sinus bradycardia, sinus tachycardia; 2. History of hyperthyroidism; 3. Have neurological or mental diseases; 4. Had taken or was currently taking opioids and non-steroidal anti-inflammatory drugs 48 hours before surgery; 5. Allergic to the study drug Esselketamine or propofol; 6. A history of addiction to opioids and asketamine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Waking time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of additional propofol;The original waking time;procedure time;heart rate after entering OR;heart rate 1 minite after induction;BP 1 minite after induction;BP after entering OR;The lowest SPO2;dizzy;VAS score before out of OR;Nausea and vomiting; | — |
Countries
China
Contacts
Public ContactHe Dan
Hengyang Maternal and Child Health Care Hospital
Outcome results
None listed