idiopathic normal pressure hydrocephalus
Conditions
Interventions
ventriculo-peritoneal shunt Group:Performing ventriculoperitoneal shunt
Modified lumbo-peritoneal shunt Group:Performing lumbar cistern - peritoneal shunt
Sponsors
Huadong Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
60 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1. Cranial CT or MRI must have an enlarged ventricular system (EI > 0.3); 2. There is a disproportionate expansion of hydrocephalus in the subarachnoid space; 3. At least clinically, gait instability or balance disorder is the main symptom, combined with cognitive decline and/or urinary incontinence; 4. There was no moderate or severe cortical atrophy, and only mild degree of white matter microangiopathopathy was accepted; 5. Agree to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Secondary Normal Pressure Hydrocephalus (sNPH) caused by secondary factors; 2. Nerve loss symptoms of other diseases lead to gait disorders; 3. Gait abnormalities caused by other skeletal motor system diseases; 4. Cognitive dysfunction and urinary and stool control disorders caused by other diseases; 5. Patients with severe spinal cord diseases were excluded because LPS shunt was not suitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin scale scores 3 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| INPH score;Perioperative complications;Mini-mental State Examination;The gait score; | — |
Countries
China
Contacts
Public ContactMao Renling
Huadong Hospital, Fudan University
Outcome results
None listed