Craniospinal Irradiation
Conditions
Interventions
Single arm optimization strategy group:Whole central radiotherapy based on high-precision dynamic radiosurgery
Sponsors
The Fifth Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
No minimum to 75 Years
Inclusion criteria
Inclusion criteria: 1. Indications for central radiotherapy; 2. ECOG physical status Score (PS) 0-2, aged = 3 months; 4. The patient must meet all of the following conditions: White blood cell count in the range of 4,000-10,000/mm3, neutrophil count >= 2,000/mm3, platelet count >= 100,000/mm3, hemoglobin >= 11.0g/dL, AST and ALT <= 1.5 times the upper limit of normal value, Total bilirubin <= 24umol/L and serum creatinine <= 85umol/L; 5. Be able to obtain complete follow-up information, understand the study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with pathological type, stage and survival status not meeting the criteria; 2. Patients who cannot tolerate radiotherapy or stop radiotherapy halfway for more than 1 week; 3. Breastfeeding and/or pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety of radiotherapy;serious side effect;Progression-Free-Survival;Overall survival;Disease Control Rate;Objective Response Rate; | — |
Countries
China
Contacts
Public ContactGuo Shuanshuan
The Fifth Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed