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Effect of cerebellar iTBS stimulation on the balance dysfunction of stroke patients and the brain remodeling mechanism

Effect of cerebellar iTBS stimulation on the balance dysfunction of stroke patients and the brain remodeling mechanism

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052590
Enrollment
Unknown
Registered
2021-11-01
Start date
2021-12-30
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Control group:sham

Sponsors

Wuxi Tongren Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Unilateral ischemic or hemorrhagic stroke; 2. Aged from 40 to 75 years; 3. Patients with stable disease and subacute stroke (onset of 1-6 months); 4. There is balance dysfunction, Berg score is between 21-55; 5. Clear cognition, able to follow simple verbal commands or instructions; 6. Patients and family members agree and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those with contraindications related to TMS and fMRI (pacemakers, intracranial implants, implanted drug pumps or pregnancy, etc.); 2. Cerebellar or brain stem stroke; 3. Patients with balance dysfunction before stroke; 4. Severe life-threatening diseases such as liver, kidney and mental illness; 5. Those who are currently participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Berg balance scale, BBS;

Secondary

MeasureTime frame
time ''up and go'' test, TUGTTUGT;Fugl-meyer Assessment Lower Extremity, FMA-LE;modified Barthel index, MBI;fMRI;

Countries

China

Contacts

Public ContactSu Bin

Wuxi Tongren Rehabilitation Hospital

13951585359@163.com+86 15306175095

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026