Benign thyroid nodule
Conditions
Interventions
experimental group A:Euthyrox, 50ug/qd
experimental group B:Euthyrox 50ug/qd + Methimazole 10mg/qd
control group C:Vitamin B1, 10mg/qd
Sponsors
Yijishan Hospital of Wannan Medical College
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Symptoms: Nodules can move up and down with swallowing, without redness, swelling, heat and pain; 2. Physical signs: One or more unilateral or bilateral thyroid nodules can be found on thyroid examination. The nodules have clear boundaries and no tenderness. They can move up and down with swallowing; 3. Imaging examination: B-mode ultrasound examination of thyroid revealed 1 or more thyroid nodules with uniform echo, absence of irregular shape and margin halo, insufficient blood supply in the nodules, no microcalcification in the nodules, needlelike diffuse or clusterlike calcification, and no abnormality in cervical lymph node ultrasound. B- ultrasonography showed three types of nodules.No suspicious ultrasound findings; 4. Aged from 20 to 60 years; 5. Nodules less than 2.5cm; 6. TSH > 1.
Exclusion criteria
Exclusion criteria: 1. Solid hypoechoic or cystic solid nodules are hypoechoic nodules in the solid component.There is abundant blood supply in the nodule; 2.It has one or more of the following ultrasonic characteristics: (1) Hypoechoic or very hypoechoic; (2) Marginal lobulation or blurring; (3) Microcalcification; (4) Aspect ratio > 1; 3. Patients with excessive thyroid nodules, obvious symptoms of compression and breathing difficulties; 4. The serum ALT and AST were 1.5 times higher than normal; 5. Pregnant and lactating women; 6. Those who cannot insist on taking the medicine; 7. Patients who require surgery; 8. Abnormal thyroid hormone; 9. Cystic nodules.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| thyroid function; | — |
Countries
China
Contacts
Public ContactGao Jialin
Yijishan Hospital of Wannan Medical College
Outcome results
None listed