Study on the effect of probiotics on improving bad breath of orthodontic children

Study on Lactobacillus plantarum and Lactobacillus salivarius in improving halitosis in orthodontic children and their regulating effects on oral flora

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052567

Enrollment

Unknown

Registered

2021-10-31

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis

Interventions

Halitosis treat group:probiotics

Halitosis placebo group:placebo

Healthy control group:baseline

Eligibility

Sex/Gender

All

Age

6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Use Halimeter to measure bad breath value above 150 PPb; 2. No systemic diseases.

Exclusion criteria

Exclusion criteria: 1. The depth of the periodontal pocket exceeds 6mm; 2. Systemic antibiotic treatment within three months or antibiotics taken within one month; 3. Current smoking habit; 4. Eat irritating foods such as garlic and shallots within 24 hours.

Design outcomes

Primary

Measure	Time frame
halimeter ppb;	—

Countries

China

Contacts

Public ContactZhang Qiuxiang

Jiangnan University

zhangqx@jiangnan.edu.cn+86 13814228495

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026