Lung protection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Elective neurosurgery was performed on patients aged from 18 to 65 years; 2. The patient was placed in a supine position; 3. The surgery lasted 3-5 hours; 4. The American Society of Anesthesiologists (ASA) grades were I-III; 5. The patients voluntarily participated and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Any cerebrovascular accident within 3 months, such as stroke, transient ischemic attack (TIA), etc.; 2. Patients with unstable angina pectoris and myocardial infarction within 3 months; 3. Laryngeal mass, obstruction, maxillofacial fracture or deformity; 4. Full stomach, high intra-abdominal pressure, habitual vomiting, gastroesophageal reflux disease; 5. Pharyngeal infection, hematoma, abscess, tonsil enlargement; 6. Upper respiratory tract infection within one month, fever, cough, runny nose, nasal congestion, etc.; 7. Chronic airway inflammation, airway hyperresponsiveness or history of asthma; 8. Seriously abnormal liver and kidney function; 9. Diabetic patients with serious diabetic complications (diabetic ketoacidosis, hyperosmolar coma, various infections, macrovascular diseases, diabetic nephropathy, retinopathy, diabetic cardiomyopathy, diabetic neuropathy, diabetic foot, etc.); 10. Severe hypertension complications, such as arterial dissection, kidney failure, cerebral hemorrhage, etc.; 11. Confirmed/suspected abuse or long-term use of narcotic sedatives and analgesics; 12. People with immune system diseases; 13. Hypothyroidism; 14. Patients with hyperkalemia; 15. Patients with serious diseases of the blood system; 16. Mentally ill persons; 17. Reoperation within 17.3 months; 18. Patients with contraindications or allergies to intraoperative drugs; 19. Patients enrolled in other studies within 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung protection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Temperature; | — |
Countries
China
Contacts
Tianjin Medical University General Hospital