Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with stroke by clinical assessment and comprehensive imaging examination met the diagnostic criteria for stroke; 2. Fugl-Meyer sensory function score proved to be sensory dysfunction (below 24 points); 3. Aged 18 to 70 years, no gender limit; 4. No cognitive impairment or communication impairment, with a mini-mental state examination (MMSE) score of 27 or more; 5. The first onset, the duration of the disease was less than 6 months.
Exclusion criteria
Exclusion criteria: 1. Those who have serious systemic diseases such as cardiopulmonary disease and cannot tolerate rehabilitation treatment; 2. Patients with diagnosed psychosis, major depression (suicidal tendency) or epilepsy, and those with a family history of psychosis or epilepsy; 3. There are influencing factors of serious systemic diseases such as diabetes and uremia; 4. According to the safety guidelines, there are contraindications for transcranial direct current/magnetic stimulation (TMS/tDCS) and functional magnetic resonance (fMRI) examinations such as metal foreign bodies in the body or other electronic devices implanted in the body, etc.; 5. Defects in hearing or vision may affect assessment and virtual reality rehabilitation; 6. Use drugs that change the excitability of the cerebral cortex (antiepileptic drugs, sedative, and hypnotic drugs, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of Fugl-meyer sensory function score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tactile threshold of the upper/lower limbs of the affected side;Two-point discrimination of the upper/lower limbs of the affected side;Upper/lower limb sensory index score of the affected side;evaluation of the joint position and motion direction of the affected upper/lower limbs;Electrophysiological examination of upper and lower limbs of affected side;Fugl-meyer balance function score;the functional magnetic resonance imaging (fMRI);mini-mental state examination;modified Ashworth score;Daily life (behavior) ability; | — |
Countries
China
Contacts
Shanghai University of Traditional Chinese Medicine