Cognitive behavioral therapy-based chatbot alleviating depressive symptoms in college students: a single-blind, randomized controlled trial

A study on the intervention effect of conversational agent for mental health problems

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052532

Enrollment

Unknown

Registered

2021-10-30

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

experimental group:Xiao E robot

control group 1:e-book

control group 2:Xiao Ai

Eligibility

Sex/Gender

All

Age

18 Years to 34 Years

Inclusion criteria

Inclusion criteria: 1. University students aged from 18 to 34 years; 2. Average score of Depression dimension in Chinese College Students' Mental Health Screening Scale is between 2 and 3; 3. No dyslexia; 4. Able to read Chinese; 5. Patients provided their written and informed consent.

Exclusion criteria

Exclusion criteria: 1. The score of any item in suicide dimension in Chinese College Students' Mental Health Screening Scale is >=3; 2. Standard score of suicide dimension or hallucination and delusion dimension of Chinese College Students Mental Health Screening Scale is >3.

Design outcomes

Primary

Measure	Time frame
PHQ-9;	—

Secondary

Measure	Time frame
Work Alliance Questionnaire;Acceptability and Usability Scale;	—

Countries

China

Contacts

Public ContactZhang Shuo

Tianjin University

zhangshuo@quesoar.com+86 15222000761

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026