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Effects of S-ketamine and propofol on emergence agitation in children under sevoflurane anesthesia

Effects of S-ketamine and propofol on emergence agitation in children under sevoflurane anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052520
Enrollment
Unknown
Registered
2021-10-30
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

emergence agitation

Interventions

control group:blank control
experimental group 1:S-ketamine was administered 5min before the end of surgery
experimental group 2:Propofol was administered 5 minutes before the end of surgery

Sponsors

Department of Anesthesiology of Xuzhou Children's Hospital, Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Children with tonsillectomy and/or adenoidectomy under elective general anesthesia; 2. Aged from 3 to 7 years; 3. Weight 12-40kg; 4. ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Allergic to S-ketamine or propofol injection; 2. Preoperative hepatic or renal insufficiency or heart disease; 3. Symptoms of upper respiratory tract infection within 1 week before surgery; 4. Children with neurological diseases; 5. The operation time was less than 10min or more than 40min.

Design outcomes

Primary

MeasureTime frame
Incidence of emergence agitation;

Secondary

MeasureTime frame
Postoperative FLACC pain score of the children;

Countries

China

Contacts

Public ContactWu Xiaole

Xuzhou Children's Hospital, Xuzhou Medical University

2401708332@qq.com+86 13912006850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026