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Transcranial Direct Current Stimulation in Post-Stroke Fatigue

Transcranial Direct Current Stimulation in Post-Stroke Fatigue: A Double-blind Randomised Control Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052515
Enrollment
Unknown
Registered
2021-10-30
Start date
2023-01-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Two groups:tDCS

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. both male and female; 2. at least 18 years old; 3. any level of education or literacy; 4. well-documented stroke occurring; 5. Chinese ethnicity and fluency in the Cantonese dialect; 6. ability and willingness to give informed consent; 7. right-handed; 8. Presence of PSF as defined by the FSS score.

Exclusion criteria

Exclusion criteria: 1. history of depression or Geriatric Depression Scale (Chau et al. 2006) score of seven or more; 2. bipolar disorder, schizophrenia and/or alcohol/substance abuse/dependence; 3. history of any neurological disease other than stroke; 4. history of epilepsy, traumatic brain injury, narcolepsy, sleep apnoea, cancer or hypothyroidism; 5. history of unexplained fainting spells as self-reported; 6. Pregnancy; 7. have had no neurosurgery as self reported; 8. dementia, defined as an MMSE score of less than 20 (Chiu et al. 1994); 9. poststroke depression, defined as the presence of major depression as assessed by a psychiatrist using the Structured Clinical Interview for DSM-IV (Kam 2000) and according to the DSM-V Diagnostic Criteria (American Psychiatric Association 2013); 10. taking medications known to inflcuence fatigue, such as hypntoics; 11. taking medications known to reduce the effect of tDCS, such as antipeileptic drugs; 12. previous or current use of tDCS; 13. contraindications to tDCS such as damaged skin at the site of stimulation, carrying a pacemaker, metal in the head, and implanted brain medical devices.

Design outcomes

Primary

MeasureTime frame
Fatigue;

Countries

China

Contacts

Public ContactTANG Wai Kwong

The Chinese University of Hong Kong

tangwk@cuhk.edu.hk+852 3919 7754

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 9, 2026