anesthesia induction
Conditions
Interventions
The morning group:Under Masimo monitoring, take TCI, set the plasma concentration of propofol to 5ug / ml, and the infusion time is 2 minutes, when the patient's Psi value is <= 50 for the first time,
The afternoon group:Under Masimo monitoring, take TCI, set the plasma concentration of propofol to 5ug / ml, and the infusion time is 2 minutes, when the patient's Psi value is <= 50 for the first tim
Sponsors
Department of Anesthesiology, The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 50 years; 2. Patients undergoing elective short surgery under general anesthesia; 3. ASA I-II?; 4. 18.5<=BMI<=28; 5. Willing to participate and able to understand and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients allergic to propofol; 2. Pregnant women or pregnant women; 3. Patients with severe cardiovascular, cerebrovascular, liver and kidney diseases; 4. Patients expected to have a difficult airway; 5. Participated in other drug trials within three months; 6. Long term use of central nervous system stimulants; 7. Patients who cannot cooperate and communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the dose of propofol;heart rate and BIS at each time point;Arterial blood pressure at each time point;electroencephalogram data; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of Masimo reaches 50 firstly;respiratory rate;propofol plasma concentration;effect-site concentration;Psi at each time point;tidal volume; | — |
Countries
China
Contacts
Public ContactChen Yupei
Department of Anesthesiology, The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed