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A prospective, single center, randomized controlled study of the effect of neorectal mucosal flap on anterior resection syndrome (ARS)

A prospective, single center, randomized controlled study of the effect of neorectal mucosal flap on anterior resection syndrome (ARS)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052495
Enrollment
Unknown
Registered
2021-10-29
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

trial group:Neorectal mucosal flap
control group:Conventional anterior rectal resection

Sponsors

Xijing Hospital, Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Male or female, aged 18 to 75 years; 2. ASA (American society of Aneshesiologists ASA physical status classification system); physical status classification I to III; 3. NRS (Nutrition risk Screening, NRS) 2002 score < 3 points; 4. ECOG (Eastern Cooperative Oncology Group, ECOG) grade 0-2; 5. Patients who received anterior rectal resection or combined prophylactic ileostomy; 6. For patients with rectal cancer, the tumor is required to be less than 12cm away from the anal verge; 7. For patients with rectal cancer, no neoadjuvant chemoradiotherapy was performed before surgery; 8. Colonoscopy showed no stenosis or obstruction in the proximal colon of the lesion; 9. Voluntarily signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Rectal cancer patients with distant organ or abdominal and pelvic metastasis; 2. Complicated with serious cardiovascular, cerebrovascular, lung, liver and kidney diseases; 3. Complicated with mental illness; 4. History of previous abdominal and pelvic surgery; 5. Previous history of chronic intestinal obstruction; 6. Previous constipation, diarrhea or severe intestinal dysfunction.

Design outcomes

Primary

MeasureTime frame
Low Anterior Resection Syndrome (LARS) Questionnaire;

Secondary

MeasureTime frame
Operation time;

Countries

China

Contacts

Public ContactHong Liu

Xijing Hospital, Air Force Medical University

hongliu1@fmmu.edu.cn+86 84771508

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026