spine disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years old; 2. ASA classification I~II; 3.BMI18.0-23.99kg/m2; 4. The expected operation time is more than 2 hours.
Exclusion criteria
Exclusion criteria: 1. The patient's auricle has infection, deformity or hearing limitation; 2. The recent history of taking drugs that affect the body's autonomic nervous system; 3. Known cognitive impairment or mental illness before surgery; 4. The patient refused to accept the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure will be measured at 1-minute intervals for 10 minutes after the administration of ephedrine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative inflammatory mediators;QoR-15 recovery quality score;AIS sleep score;VAS pain score;nausea and vomiting score;first time out of bed after operation; | — |
Countries
China
Contacts
Southeast University