sellar region tumor
Conditions
Interventions
transseptal group:bilateral transseptal approach
standard endoscopic group:standard endoscopic transnasal approach
Sponsors
Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. aged 18-70 years old, junior high school education or above; 2. The clinical symptoms, signs, and imaging are consistent with the diagnosis of sellar tumor for the first time surgery patients, and there are clear indications for transsphenoidal surgery; 3. Inpatients awaiting surgery who have no contraindications to surgery after admission examination and evaluation; 4. Sign the informed consent for surgery and the informed consent for clinical trials.
Exclusion criteria
Exclusion criteria: 1. Obvious history of neuropsychiatric and physical serious diseases (including cardiovascular and cerebrovascular accidents, serious trauma, mental diseases, and other systemic tumor diseases) before treatment; 2. Have a clear history of nasal surgery, including nasal surgery such as tumor resection through nasal sella, rhinoplasty, correction of nasal septum deviation, removal of nasal polyps, sinusitis flushing, etc.; 3. There is a clear history of nasal diseases that affect the evaluation of smell, including nasopharyngeal tumors, nasal trauma, atrophic rhinitis, suppurative sinusitis, etc.; 4. AD/PD patients or other causes of preoperative hyposmia, disorders or allergies; 5. The tumor expanded significantly to the suprasellar, and the nasal septum mucosal flap should be used to repair the cerebrospinal fluid leakage during the operation; 6. Pregnant women; 7. Those who have participated in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nasal structure;nasal function;Quality of Life; | — |
Secondary
| Measure | Time frame |
|---|---|
| surgical outcome;endocrine outcome; | — |
Countries
China
Contacts
Public ContactYang Bojie
Neurosurgery, Huashan Hospital Affiliated to Fudan University
Outcome results
None listed