awake endotracheal intubation
Conditions
Interventions
Control Group:nebulized 2% lidocaine 10ml+ 1ml normal saline
Test group 1:nebulized 2% lidocaine 10ml+0.5µg/kg dexmedetomidine was dissolved in normal saline for 1mL
Test group 2:nebulized 2% lidocaine 10ml+1.0µg/kg dexmedetomidine was dissolved in normal saline for 1mL
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-65 years; American Society of anesthesiologists (ASA) grade 1-2; Adult patients requiring awake endotracheal intubation such as difficult airway, full-stomach, obstructive sleep apnea syndrome, and other causes.
Exclusion criteria
Exclusion criteria: Severe hypertension; Valvular heart disease and ischemic heart disease; Severe bradycardia (<50 times/min), atrioventricular block; Bronchial asthma, bronchiectasis, chronic obstructive pulmonary disease; Mental and neurological diseases; Nasal bone fracture, nasal trauma, skull base fracture, intracranial infection; Allergic to drugs used; seriously abnormal liver and kidney function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Observer's Assessment of Alertness/Sedation (OAA/S);Heart rate, mean arterial pressure, pulse oximetry;Intubation tolerance score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of successful intubation;Intubation satisfaction score;Stress response related indicators; | — |
Countries
China
Contacts
Public ContactWang Liwei
Xuzhou Central Hospital
Outcome results
None listed