carbon monoxide poisoning
Conditions
Interventions
mask oxygen group:Nil
Non-invasive positive pressure ventilation group:Nil
Sponsors
Liaocheng People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients had a clear history of CO exposure and met the diagnostic criteria of severe CO poisoning: 1. The degree of disturbance of consciousness was deep coma or cerebral decortex state. 2. Patients with disturbance of consciousness and complicated with any of the following manifestations: brain edema; shock or severe myocardial damage; pulmonary edema; respiratory failure; upper gastrointestinal bleeding; brain lesion, such as impaired signs of pyramidal system or extrapyramidal system. 3. The concentration of COHB could reach as high as 50%. 4. Patients without contraindications of hyperbaric oxygen and noninvasive ventilator.
Exclusion criteria
Exclusion criteria: Patients with severe mental illness, severe cerebrovascular disease (such as cerebral hemorrhage or massive cerebral infarction), severe heart disease and severe respiratory disease before CO poisoning were excluded; patients with contraindications of hyperbaric oxygen and noninvasive ventilator, as well as mild and moderate CO poisoning were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| carboxyhemoglobin;The incidence of respiratory failure;Incidence of late-onset encephalopathy;consciousness recovery time;recovery of cadponin I; | — |
Countries
China
Contacts
Public ContactYu Zhongkai
Liaocheng People's Hospital
Outcome results
None listed