lung cancer
Conditions
Interventions
Group 1:Video-assisted thoracoscopic surgery under tubeless anesthesia
Group 2:Video-assisted thoracoscopic surgery under intubation under general anesthesia
Sponsors
the First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Young and middle-aged group (18-59 years old): preoperative blood pressure and blood sugar are normal; no history of cerebral ischemia, cerebral infarction, no history of craniocerebral surgery and brain dysfunction, no history of mental and psychological disorders and medication; No history of gastrointestinal diseases, surgery, or immune-related diseases; no history of severe pain or continuous use of painkillers in the past 3 months; no history of alcoholism in the past 1 year; no malnutrition, no blindness or deafness; preoperative heart and lung function Normal, no history of allergy to anesthetics; wedge resection or lobectomy preparation for lung cancer admission; no contraindications for preoperative MRI, EEG and cerebral blood flow examination; 2. Elderly group (>=60 years old): preoperative blood pressure and blood sugar were normal, no obvious symptoms of cerebral infarction; no previous history of mental or psychological disorders or medication; no previous history of gastrointestinal diseases and surgery; preoperative heart and lung function No surgical contraindications; wedge resection or lobectomy preparation for lung cancer admission; no contraindications for preoperative MRI, EEG and cerebral blood flow examination; agreed to participate in the experimental group after communication.
Exclusion criteria
Exclusion criteria: 1. Obese patients with body mass index (BMI) >= 28kg/m2; 2. Anesthesia risk classification of American Society of Anesthesiology is above grade III; 3. Mallampati airway classification >= grade 3; 4. Gastrointestinal diseases have a high risk of reflux and gastrointestinal dysfunction; 5. Have a history of sleep apnea.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain Physiological Multimodal; | — |
Secondary
| Measure | Time frame |
|---|---|
| cerebral blood flow;Brain electrophysiology;cerebral oxygen metabolism; | — |
Countries
China
Contacts
Public ContactHe Jianxing
the First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed