Rectal cancer
Conditions
Interventions
experimental group:Transanorectal total mesorectal excision
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged 18-75 years; 2. Biopsy pathology confirmed rectal adenocarcinoma; 3. MRI and/or rectosigmoid endoscopy showed that the distance between the lower edge of the tumor and the anal verge was less than or equal to 5cm; 4. High-resolution MRI judges rectal cancer as T2-T3b, N0; 5. No distant metastasis of tumor in preoperative examination; 6. ECOG (Eastern Cooperative Oncology Group) determines the clinical condition as grade 0-2; 7. Subjects signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Radiotherapy and chemotherapy for rectal cancer before enrollment; 2. History of other tumors, non-adenocarcinoma rectal malignant tumor or rectal malignant tumor occurring on the basis of inflammatory bowel disease; 3. Emergency surgery is required due to intestinal obstruction, perforation, bleeding, etc.; 4. Pregnant and lactating women; 5. The investigator judges that the compliance is poor or not suitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local Recurrence;Overall survival;disease free survival;anal function; | — |
Secondary
| Measure | Time frame |
|---|---|
| R0 resection rate;Quality of surgical specimen;Surgical complications within 30 days; | — |
Countries
China
Contacts
Public ContactZheng Jianyong
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed