Study on brain plasticity of stroke patients by bCI upper limb rehabilitation system based on motor imager

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052452

Enrollment

Unknown

Registered

2021-10-26

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strok

Interventions

BCI group:MI-BCI upper limb rehabilitation

control group:Routine rehabilitation therapy+ shame BCI therapy

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for stroke in the Chinese Classification of Cerebrovascular Diseases in 2015, and at the same time, the brain MRI and CT are clear, the first onset or previous stroke but no sequelae; 2. Aged 18 to 80 years, gender is not limited; 3. duration of disease 1 to 3 months; 4. There is hemiplegia on one side of the limb, and the modified Ashworth Scale (MAS) grading of the affected side flexor and extensor muscle tension is less than or equal to 1+; 5. Stage I= grade 2; 7. Consent and sign the informed consent form for treatment.

Exclusion criteria

Exclusion criteria: 1. Those whose vital signs are still unstable, who are in danger of life or have functional failure of important organs (such as heart, lung, liver, kidney, etc.); 2. Severe cognitive impairment (MMSE<=21 points), speech impairment, visual impairment, hearing impairment, complete aphasia, unable to understand and complete the therapist's instructions; 3. Those with metal implants such as stents, etc.; 4. Those who use implantable electronic devices (such as pacemakers); 5. Patients with epilepsy or diagnosed secondary epilepsy; 6. Active tumor patients; 7. Severe allergy to conductive adhesive; 8. Pregnant women; 9. Those who have a history of severe mental disorders in the past or are unable to cooperate; 10. Patients with limb dysfunction caused by other reasons before the onset; 11. Those who cannot cooperate with active training for other reasons refuse to sign the informed consent form for treatment.

Design outcomes

Primary

Measure	Time frame
functional magnetic resonance imaging, fMRI;diffusion tensor imaging, DTI;Fugl-Meyer upper extremity score (UEFM);Barthel Index (BI);	—

Secondary

Measure	Time frame
Wolf Motor Function Test (WMFT);Motor Assessment Scale (MAS);Montreal cognitive assessment (MoCA-Beijing version);Hamilton Depression Scale (HAMD);	—

Countries

China

Contacts

Public ContactYe Xiangming

Zhejiang Provincial People's Hospital

yexmdr@hotmail.com+86 13750814756

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026