Hematological diseases complicated with pulmonary infection
Conditions
Interventions
Sponsors
Hematology Hospital of Chiese Academy of Medical Sciences(Institute of Hematology Chinese Academy of Medical Sciences)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age: >=18 years old; 2. Underlying diseases: (1) Patients with acute leukemia/myelodysplastic syndrome/aplastic anemia complicated with neutropenia, or expected to have agranulocytosis for more than 10 days; (2) Continuous immunosuppressive therapy after allogeneic hematopoietic stem cell transplantation in patients with hematological malignancies; 3. Lung CT showed atelectasis; lung nodules, consolidation, ground glass, cord or patch shadows; diffuse lung lesions were considered in patients with pulmonary infection.
Exclusion criteria
Exclusion criteria: 1. Inability to tolerate pulmonary bronchoscopy; 2. Not signing informed consent; 3. Patients with other inappropriate inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sputum mNGS;Bronchial lavage fluid mNGS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gram staining and acid fast staining of sputum smears;Bronchial lavage smears were stained with gram and acid fast;Blood GM test;Bronchial lavage fluid GM test;Blood G test;Bronchial lavage fluid X-Pert; | — |
Countries
China
Contacts
Public ContactJiang Erlie
Hematology Hospital of Chiese Academy of Medical Sciences(Institute of Hematology Chinese Academy of Medical Sciences)
Outcome results
None listed