Skip to content

Imaging genomics Biomarker mining for T790M mutation and prognostic evaluation of EGFR-TKI in advanced NSCLC

Imaging genomics Biomarker mining for T790M mutation and prognostic evaluation of EGFR-TKI in advanced NSCLC

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052437
Enrollment
Unknown
Registered
2021-10-26
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Progress group VS effective group:Nil

Sponsors

Huadong Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Lung cancer patients with stage III-IV in the eighth edition of the TNM staging of lung cancer; 2. Aged 18 to 75 years old; 3. The mutation status of the EGFR driver gene can be obtained; 4. All received EGFR-TKI first-line or combination therapy; 5. CT image data can be obtained before treatment and after 1 year of treatment.

Exclusion criteria

Exclusion criteria: 1. Previous cancer patients, patients who received lung resection during treatment, those who received radiotherapy and chemotherapy before surgery, etc.; 2. Serious comorbidities, such as heart function class III/IV, history of deep vein thrombosis or pulmonary embolism, liver and renal insufficiency; 3. Other situations that the investigator considers unsuitable to participate in this trial; 4. Lost to follow-up data and data of death from non-endpoint disease.

Design outcomes

Primary

MeasureTime frame
Imaging genomic biomarkers;

Countries

China

Contacts

Public ContactChen Wufei

Huadong Hospital affiliated to Fudan University

chenwufei_2008@163.com+86 18721519871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026