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A randomized controlled trial of percutaneous electrical stimulation for functional dyspepsia

A randomized controlled trial of percutaneous electrical stimulation for functional dyspepsia and its immunomodulatory mechanism

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052404
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-12-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional dyspepsia

Interventions

The experimental group:Percutaneous electroacupuncture stimulation(ST36, PC6)
The control group:Percutaneous electroacupuncture stimulation(sham ST36, sham PC6)

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for functional dyspepsia Rome IV postprandial discomfort syndrome or epigastric pain syndrome; 2. Aged 18-65 years old, male or female; 3. Gastroscopy should be performed in a tertiary hospital within one year before the selection to exclude gastric cancer, ulcer, erosive gastritis or other gastric organic diseases; 4. Hepatobiliary and pancreatic diseases have been excluded by B-ultrasound examination in a top-three hospital within one year before the selection; 5. Willing to sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those with a history of abdominal surgery; 2. Take PPI, prokinetic, anticholinergic or dopaminergic drugs 2 weeks before and during the experiment; 3. Those with a history of diabetes, thyroid disease, systemic sclerosis, systemic lupus erythematosus, etc.; 4. Pregnant women, lactating women or those planning to become pregnant; 5. Those who are allergic to skin preparations and familiar with acupoints and functions.

Design outcomes

Primary

MeasureTime frame
Symptom scores;Peripheral blood cytokines;The number of eosinophils and mast cells in gastroduodenal mucosa;

Secondary

MeasureTime frame
Cognitive scale measurement;

Countries

China

Contacts

Public ContactHu Xiangpeng

The Second Affiliated Hospital of Anhui Medical University

xphuay2003@aliyun.com+86 18756039192

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026