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The median effective dose(ED50) of ropivacaine in extending epidural analgesia for emergency cesarean section

The median effective dose(ED50) of ropivacaine in extending epidural analgesia for emergency cesarean section

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052386
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Epidural Anesthesia Group:Injecting 0.75% ropivacaine into epdirual space by epidural catheter
Combined spinal and epidural anesthesia:transfer combined spinal and epidural anesthesia

Sponsors

Guangdong Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Maternal age >=18 years old, singleton pregnancy, no contraindications in intrathecal anesthesia, and in epidural labor analgesia.

Exclusion criteria

Exclusion criteria: 1. 1.1 emergency cesarean section (grade 1: immediate danger to the life of the mother and fetus; grade 2: damage to the mother and fetus, but no life-threatening; grade 3: delivery is required, but there is no damage to the mother and fetus); 2. Epidural catheter falls off during labor analgesia; 3. Burst pain >= 3 times during labor analgesia; 4. VAS score during labor analgesia > 4 points; 5. The epidural catheter is deviated to one side or inserted into a blood vessel or into the subarachnoid space; 6. History of local anesthetic allergy; 7. Contraindications of spinal anesthesia: abnormal coagulation function, history of lumbar trauma, uncooperative mental illness, etc.; 8. Patients who are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Block plane;

Countries

China

Contacts

Public ContactJia Jie

Guangdong Maternal and Child Health Hospital

jiajie8712@sina.com+86 13828459960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026