Research on pancreatin supplement therapy for critically ill adults

Study on the improvement of pancreatic enzyme supplementation on the nutritional status of adult severely ill patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052385

Enrollment

Unknown

Registered

2021-10-24

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critically ill

Interventions

Pancreatin use group:give pancreatin

no pancreatin group:no pancreatin

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: All aged over 18 years old, without primary pancreatic disease, with two or more high risk factors for exocrine pancreatic insufficiency (PEI), receiving enteral nutrition (including basic diet), and expected ICU (EICU or SICU) hospital stay >= 7 day in critically ill patients.

Exclusion criteria

Exclusion criteria: 1. Patients in a long-term vegetative state; 2. Patients with end-stage tumors; 3. Patients with chronic wasting disease; 4. Patients with acute infectious diseases or mental illness; 5. Patients who refuse life support treatment although they have the ability to survive; 6. Pregnant or lactating women; 7. Inability to tolerate EN >= 3 days.

Design outcomes

Primary

Measure	Time frame
Rectus femoris cross-sectional area;	—

Secondary

Measure	Time frame
Serum retinol protein;Prealbumin;	—

Countries

China

Contacts

Public ContactMa Lijie

Shanghai Tenth People's Hospital

18917684027@189.cn+86 18917684027

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026