oral and maxillofacial surgery
Conditions
Interventions
group A :Ornidazole drug
group B :Metronidazole Sodium Chloride Injection
group C :Tinidazole Glucose Injection
Sponsors
The Third Affiliated Hospital of Air Force Medical University, PLA
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged above 18 years old and below 65 years old; 2. Resection of oral cavity, tongue, neck tumor, etc. (through the oropharyngeal mucosa); 3. No pre-hospital infectious diseases, and no other anti-anaerobic drugs within two weeks before surgery; 4. No hematopoietic, digestive system, autoimmune system, cardiovascular system and other diseases; 5. No symptoms of infection in the whole body; 6. No surgical contraindications; 7. The surgical incision is Class II or Class III; 8. No history of drug allergy; 9. The operation time should not exceed 6 hours; 10. Patients voluntarily participated in this study, signed the informed consent, and were able to cooperate with clinical follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with severe trauma and mental illness; 2. Women who are pregnant or breastfeeding; 3. Those who fail to use up the drug as required; 4. Intellectual disability, mental disorder; 5. Women who are planning to become pregnant, pregnant or breastfeeding and cannot strictly contracept during the test; 6. Participated in other clinical trials within the past 1 month; 7. The investigator believes that it is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of infection in surgical incisions; | — |
Countries
China
Contacts
Public ContactFeng Bin
The Third Affiliated Hospital of PLA Air Force Military Medical University
Outcome results
None listed