Diabetic retinopathy
Conditions
Interventions
M1 group:Continuous pumping mivacurium 3µg/(kg · min)
M2 group:Continuous pumping mivacurium 6µg/(kg/min)
M3 group:Continuous pumping mivacurium 9µg/(kg/min)
Sponsors
Beijing Tongren Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients who voluntarily participate in the clinical study, and written informed consent should be obtained; 2.Patients undergoing fundus surgery under general anesthesia in day ward; 3.ASA I~II; 4.The age ranges from 18 to 65; 5.BMI 18.5~28 kg/m2; 6.predicted surgical duration less than 2 hours.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, brain, liver, kidney, lung, endocrine diseases, electrolyte imbalance, anemia, and severe infection; 2. Patients with obviously difficult airway; history of chronic allergic diseases; history of mental illness, alcoholism or long-term use of psychotropic drugs and chronic analgesics; 3. Patients with neuromuscular system diseases and taking drugs that can affect neuromuscular conduction function; 4. Patients with trauma, surgical history, hypoplasia, deformity, etc. affecting the detection of muscle relaxation at the monitoring site of muscle relaxation; 5. Allergy to the test drug or other contraindications; pregnant and lactating women; 6. Participated in other clinical studies within the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time between withdrawal of muscle relaxants and recovery of TOFr to 90%; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of TOFr < 70% at extubation;Incidence of TOFr < 90% at extubation;Residence time in PACU;Departure time;Extubation time;dose of Intravenous anesthesia;Postoperative muscle relaxation depth;Adverse reactions;PACU score; | — |
Countries
China
Contacts
Public ContactWang Guyan
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed