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To explore the improvement mechanism of acupuncture on oocyte quality in patients with phlegm dampness PCOS based on follicular fluid exocrine lncrna sequencing

To explore the improvement mechanism of acupuncture on oocyte quality in patients with phlegm dampness PCOS based on follicular fluid exocrine lncrna sequencing

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052331
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Phlegm dampness polycystic ovary syndrome

Interventions

test group:Women with PCOS with Phlegm-Dampness Syndrome
Control group:Non-PCOS of non-phlegm-damp syndrome type is due to infertility due to fallopian tube factors alone or female infertility due to male factors

Sponsors

Reproductive and Genetic Center of Integrated Traditional Chinese and Western Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for the PCOS group: meet the diagnostic criteria for polycystic ovary syndrome in Western medicine and the differentiation criteria for phlegm-damp syndrome and liver-stagnation syndrome in traditional Chinese medicine; 2. Inclusion criteria for the normal control group: (1) Infertile patients with non-PCOS and normal ovarian reserve, who can ovulate normally, are infertile due to tubal factors alone; (2) Married women aged 25-40; (3) Meet the indications for IVF-ET; (4) The reproductive needs meet the requirements of the ethics committee; (5) Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with premature ovarian failure, ovarian hypofunction, uterine fibroids, endometriosis, hyperprolactinemia and other diseases; 2. Chromosomal abnormalities; 3. Those who suffer from severe mental disorders, acute infections of the urogenital system, or sexually transmitted diseases; 4. Those suffering from cardiovascular and cerebrovascular diseases, liver and kidney diseases or disorders of hematopoietic and coagulation systems; 5. Those with serious bad habits such as drug addiction; 6. Those who have used hormone drugs in the past three months.

Design outcomes

Primary

MeasureTime frame
lncRNA;

Countries

China

Contacts

Public ContactWu Haicui

Shandong University of traditional Chinese Medicine

haicui_w@163.com+86 15069129571

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026