none
Conditions
Interventions
experimental group:Stepped Hypoxia
Sponsors
Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
19 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. Healthy adults aged 18 ~ 45 years old, with balanced and reasonable gender distribution; 2. Subject: carbon monoxide hemoglobin COHb 10g / dl; 5. No smoking history / no smoking history; 6. No previous history of cardiopulmonary disease; 7. Those who pass the physical examination; 8. Subjects voluntarily participate in clinical trials and voluntarily sign written informed consent.
Exclusion criteria
Exclusion criteria: 1. Smokers or those exposed to high carbon monoxide content; 2. Those with coagulation dysfunction or artificial blood vessels; 3. Those with previous cardiopulmonary diseases; 4. There is skin disease, infection or trauma around the measurement site, which makes the parameter unable to be measured; 5. Patients with mental illness, epilepsy or other diseases leading to involuntary movement of the body; 6. Physical condition will lead to the increase of methemoglobin; 7. If the operation carried out during the clinical trial may cause excessive medical risk to the subjects, such subjects shall be excluded; 8. Pregnant women; 9. Those with grey nails; 10. The clinical trial personnel judge that the compliance is not good and cannot strictly implement the scheme; 11. Subjects are enrolled in other clinical trials within 30 days; 12. There are other diseases that are not suitable for clinical trial; 13. Unwilling to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| regional cerebral tissue oxygen saturation (rSO2 ); | — |
Countries
China
Contacts
Public ContactZongze Zhang
Zhongnan Hospital of Wuhan University
Outcome results
None listed