anesthesia gastrointestinal endoscopy procedures
Conditions
Interventions
Test group:the sequential method was used to definte the appropriate dose of anesthesia/sedation plan of the "Esketamine and Remifentanil"
Sponsors
Yangzhou Jiangdu People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Perform simple gastroscopy; 2. There are no contraindications for painless gastroscopy; 3. American Society of Anesthesiologists (ASA) classification I-II; 4. No neurological abnormalities or family history of mental illness; 5. All voluntarily participate and sign the informed consent; 6. Complete communication skills, normal hearing and smooth response; 7. Aged 18 to 60 years.
Exclusion criteria
Exclusion criteria: 1. Plan to perform endoscopic diagnosis and treatment techniques with complex operation or noxious stimulation (such as retrograde cholangiography (ERCP), endoscopic ultrasonography (EUS), endoscopic mucosal resection resection, EMR), endoscopic submucosal dissection (ESD), peroral endoscopic myotomy (POEM), enteroscopy, upper gastrointestinal foreign body removal, esophageal varices cuff ligation, upper gastrointestinal hemostasis, esophageal stricture dilation, etc.); 2. Patients with dysfunction of important organs such as the heart, liver and kidney; 3. Patients who are pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate (sedation success is defined as the completion of the whole gastroscope diagnosis and treatment operation, without the occurrence of other circumstances that meet the sedation failure standard, such as receiving sedative remedy drugs; sedation success rate is the proportion of sedation successful;The target sedation depth is the deep sedation level;Sedation induction time(the time from the start of sedation induction to the start of painless gastroscopy diagnosis and treatment, that is, the time from the start of sedation induction to the MOAA/S score <=1);After successful induction, when the gastroscope enters the endoscope, the incidence and order of severityof swallowing, body movement, and coughing movements;During the diagnosis and treatment, the incidence and severity of swallowing, body movement, and coughing movements;The incidence and order of severityof adverse events during the perioperative period; | — |
Countries
China
Contacts
Public ContactXu Nan
Yangzhou Jiangdu People's Hospital
Outcome results
None listed