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Noninvasive assessment of tissue oxygenation of periodontal inflammation by optical spectroscopy.

Noninvasive assessment of tissue oxygenation of periodontal inflammation by optical spectroscopy.

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052306
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-09-30
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

3:initial periodontal therapy

Sponsors

Peking University School and Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria of healthy control group: good oral hygiene, calculus index = 0, no swelling of gums, bleeding index 1, probing depth =4 mm, clinical attachment loss of >=1 mm, bleeding index >=2 mm, no periodontal treatment history for at least 6 months, continuous dentition except the third molar, and systemically healthy.

Exclusion criteria

Exclusion criteria: (1) use of anti-inflammatory drugs, antibiotics and immunosuppressants in the past 6 months; (2) systemic diseases that may interfere with the progression of periodontal diseases, such as diabetes and immune diseases; (3) Gingival lesions unrelated to plaque; (4) Use of orthodontic appliances; (5) Pregnancy and lactation; (6) Periodontal treatment in the past 6 months; (7) Continuous use of mouthwash containing antibacterial agent in the past 2 months; (8) Smoking; (9) The surface of attached gingiva and mucosa was stained.

Design outcomes

Primary

MeasureTime frame
Oxygenated hemoglobin;

Secondary

MeasureTime frame
Deoxyhemoglobin;

Contacts

Public ContactLuan Qingxian

Peking University School and Hospital of Stomatology

kqluanqx@126.com+86 010 82195374

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026