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Effect of low opioid multimodal analgesia on postoperative recovery quality in elderly patients: a single center, prospective, randomized, controlled study

Effect of low opioid multimodal analgesia on postoperative recovery quality in elderly patients: a single center, prospective, randomized, controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052294
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative multimodal analgesia program for elderly patients

Interventions

Control group:Control group analgesia
Experimental group:Analgesia in the experimental group

Sponsors

Yantai Yuhuangding Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. ASA II or III; 2. Aged 65-85 years; 3. Patients with elective laparoscopic or open upper abdominal surgery (stomach, gallbladder, liver, pancreas, spleen) whose operation time is longer than 1.5 hours; 4. Clear consciousness and active cooperation, can understand pain visual analog scale (VAS) score, sedation score, etc. after short training, and can use PCA device autonomously.

Exclusion criteria

Exclusion criteria: 1. Severely abnormal cardiac function; 2. Chronic respiratory insufficiency; 3. Serious abnormality of liver and kidney function (alanine aminotransferase is 3 times higher than normal or creatinine is higher than normal); 4. Suffering from central nervous system and psychological diseases, history of chronic pain, long-term use of sedatives, antidepressants, alcoholism, drug dependence, etc. before surgery, there is a risk of central respiratory depression.

Design outcomes

Primary

MeasureTime frame
mean arterial pressure;heart rate;blood oxygen saturation;wake up time;visual analogue scale pain and sedation score;postoperative gastrointestinal function;postoperative recovery;

Countries

China

Contacts

Public ContactDu Juan

Yantai Yuhuangding Hospital

641181767@qq.com+86 13583522560

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026