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Safety and efficacy of Butorphanol in lower abdominal surgery: a multicenter, randomized, open-label, positive controlled pragmatic clinical trial

Safety and efficacy of Butorphanol in lower abdominal surgery: a multicenter, randomized, open-label, positive controlled pragmatic clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052284
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-10-18
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group A:Routine anesthesia and analgesia regimen
Group B:Butorphanol analgesia
Group C:Butorphanol induction

Sponsors

The Second Affiliated Hospital of Zunyi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 years; 2. ASA classification I-II; 3. Body mass index: 18-25.

Exclusion criteria

Exclusion criteria: 1. Incomplete records of data and case data; 2. Serious adverse drug reactions; 3. Patients and their family members request to withdraw halfway; 4. Patients with unstable circulation during operation and sent to ICU after operation; 5. The operation time is more than 6h.

Design outcomes

Primary

MeasureTime frame
Intraoperative body movement;Spontaneous breathing recovery time;Extubation time;Residence time in resuscitation room;Choking after extubation;Laryngeal spasm after extubation;Agitation after extubation;Secondary intubation;Nausea and vomiting;Allergic reaction;Incidence of respiratory depression;Analgesia visual analogue score;Press times of postoperative analgesia pump;Remedial drug dose;Ricker sedation agitation score;Blood sugar;Lactic acid;Cortisol;Adrenaline;ß- endorphins;C-reactive protein;Sleep time;

Secondary

MeasureTime frame
Heart rate;Systolic pressure;Diastolic pressure;Mean arterial pressure;Blood oxygen saturation;

Countries

China

Contacts

Public ContactZhang Yi

The Second Affiliated Hospital of Zunyi Medical University

cherishher@126.com+86 15329716676

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026