mediastinal lesions
Conditions
Interventions
Gold Standard:1. The gold standard for malignant tumors: the pathological results of ultrasound-guided transbronchial forceps biopsy or surgery
2. Benign disease gold standard: all patients diagnosed with benign disease were followed up for more than 6 months, and the final diagnosis was made by an expert panel based on cl
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 16 years; 2. Chest imaging examination indicates the presence of mediastinal lesions in at least one site (short diameter >=10mm); 3. After improving laboratory examinations, imaging examinations, routine bronchoscopy and TBNA examinations, the diagnosis cannot be made; 4. Tumors are considered after TBNA but the specimens are insufficient for immunohistochemistry, genetic testing, etc.; 5. Informed consent to participate in this clinical study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Contraindications related to bronchoscopy such as severe cardiopulmonary disease, coagulation dysfunction, anesthesia intolerance, mental illness or severe neurosis; 2. Mediastinal lesions were not detected by intraoperative ultrasound bronchoscopy; 3. Intraoperative ultrasound found that the risk of biopsy is high, and it is not suitable to continue biopsy, such as lesions with rich blood flow or close to large blood vessels; 4. The lesions are cysts or abscesses; 5. Participated in other clinical trials in the last 3 months; 6. Unable to cooperate with the study for any reason or the investigator thinks it is not suitable to be included in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic efficiency;Biopsy success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The sample quality;Size of specimen; | — |
Countries
China
Contacts
Public ContactGuo Shuliang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed