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A multicenter research project of genome variant information detection by the shallow whole-genome sequencing (sWGS) technique in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) patients

A multicenter research project of genome variant information detection by the shallow whole-genome sequencing (sWGS) technique in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052276
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-11-08
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myeloid leukemia (AML)

Interventions

case series:None

Sponsors

The Affiliated Cancer Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Diagnose newly diagnosed AML, MDS or MDS secondary AML patients according to the 2016 WHO diagnostic criteria; 2. Aged 18-75 years; 3. AML patients need to undergo karyotype analysis; 4. MDS patients need to undergo chromosomal karyotype analysis and FISH (-5/5q-, -7/7q-, +8, 20q-, -Y (male, but not female)) detection; 5. Physical fitness score 0-3 (WHO standard).

Exclusion criteria

Exclusion criteria: 1. Suffering from malignant tumors of other organs at the same time; 2. There are other conditions that hinder the research.

Design outcomes

Primary

MeasureTime frame
Copy number aberration(CNA);—

Countries

China

Contacts

Public ContactSong Yongping

The Affiliated Cancer Hospital of Zhengzhou University

songyongping001@126.com+86 13803846526

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026