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Characteristics of gut microbiota and metabolites in the development of gestational diabetes mellitus and their effects on offspring

Characteristics of gut microbiota and metabolites in the development of gestational diabetes mellitus and their effects on offspring

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052265
Enrollment
Unknown
Registered
2021-10-24
Start date
2021-10-12
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gestational diabetes mellitus

Interventions

Sponsors

The People's Hospital of Xishan, Wuxi
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Early pregnancy pregnant women aged 18-45 years(less than 16 weeks pregnant); 2. Those who voluntarily participated and signed the informed consent form were taken as the research subjects; 3. The inclusion criteria of the gestational diabetes group were based on the diagnostic criteria of the 75g OGTT International Diabetes and Pregnancy Study Group and met at least one of the following criteria: (1) Fasting blood glucose (FPG) >= 5.1 mmol/l; (2) 1 h glucose >= 10.0 mmol/l; (3) 2 h glucose >= 8.5 mmol/l; 4. Pregnant women diagnosed with GDM have not been treated with insulin; 5. The control group is a 1:1 matched group with normal blood glucose screening test.

Exclusion criteria

Exclusion criteria: 1. Have a chronic medical condition, including high blood pressure, type 2 diabetes, heart or kidney disease. 2. Patients have reported use of antibiotics or drugs that affect the stomach or intestinal microbiota within 2 months prior to enrollment. 3. Poor patient compliance and poor follow-up possibility.

Design outcomes

Primary

MeasureTime frame
gut microbiota;plasma glucose;

Countries

China

Contacts

Public ContactWang Gang

Jiangnan University

wanggang@jiangnan.edu.cn+86 15852818722

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026