Ovarian Cancer
Conditions
Interventions
Sponsors
Obstetrics and Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Females aged 18-80 years; 2. FIGO stage II ovarian cancer: Ultrasound and CT showed suspicious adnexal mass (unilateral or bilateral) or surgically confirmed ovarian cancer (unilateral or bilateral salpingo-oophorectomy with or without hysterectomy); 3. Negative lymph nodes on preoperative imaging, defined as the largest diameter of lymph nodes < 1 cm; 4. Proper respiratory, liver, heart, bone marrow, liver and kidney function; 5. Have not received any treatment related to the disease before this study, including surgery, chemotherapy, radiotherapy and other anti-tumor drug treatment; 6. Have complete clinical data, such as imaging data to evaluate tumor size, location, clinical stage, tumor markers CEA, CA19-9, CA125, etc.; 7. Patients voluntarily joined the study and signed the informed consent for clinical specimen sampling; 8. Female patients of childbearing age must have a negative HCG test; and must be non-breastfeeding.
Exclusion criteria
Exclusion criteria: 1. Extra-pelvic spread on initial imaging or surgical exploration and confirmed stage III or IV; 2. Previous vascular surgery of the aorta, inferior vena cava and/or blood vessels; 3. Previous lymph node dissection or lymph node sampling in the pelvic or para-aortic area; 4. The subject has suffered from other malignant tumors such as malignant lymphoma, abdominal malignant tumor, etc. in the past 5 years or at the same time; 5. History of hypersensitivity to colloid, indocyanine green (ICG), iodine, iodine dyes, isoendosulfan blue or triphenylmethane; 6. According to the judgment of the researcher, the subjects have other factors that may lead to the forced termination of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic sensitivity;Diagnostic specificity;Sentinel lymph node detection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety;Feasibility; | — |
Countries
China
Contacts
Public ContactYao Liangqing
Obstetrics and Gynecology Hospital of Fudan University
Outcome results
None listed