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Analysis of the curative effect of vital pulp therapy in the treatment of dental pulp injury caused by caries of permanent teeth, a non-inferiority randomized controlled clinical study

Analysis of the curative effect of vital pulp therapy in the treatment of dental pulp injury caused by caries of permanent teeth, a non-inferiority randomized controlled clinical study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052248
Enrollment
Unknown
Registered
2021-10-23
Start date
2021-11-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

caries-derived pulp injury of permanent teeth

Interventions

Experimental group:marrow preservation therapy
Control group:root canal therapy

Sponsors

Shanghai Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. The maxillary or mandibular first and second molars whose root tips have been developed; 2. The teeth can be detected and deep caries; 3. Diagnosed as partially irreversible pulpitis.

Exclusion criteria

Exclusion criteria: 1. Irreversible pulpitis due to wear, wedge-shaped defect, cracked tooth, periodontal disease, etc.; 2. Those who took antibiotics and painkillers before seeing a doctor, and those who could not elicit symptoms during the inspection; 3. The tooth has undergone pulp preservation or root canal therapy; 4. Moderate to severe periodontitis or furcation lesions; 5. X-ray see periapical transmission; 6. Pregnant patients, serious systemic diseases, mental disorders or unable to cooperate with treatment.

Design outcomes

Primary

MeasureTime frame
Surgical treatment success rate 1 year after operation;

Secondary

MeasureTime frame
Pain frequency and pain scale score within 1 week after operation;Crown discoloration ratio;Patient quality of life score;Intraoperative operation time;

Countries

China

Contacts

Public ContactWei Xiaoling

Shanghai Stomatological Hospital

Xiaoling_wei@fudan.edu.cn+86 136 3637 7352

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026