Benign pyloric and duodenal obstruction
Conditions
Interventions
Experimental group:partitioning gastrojejunostomy with "highly selective vagolomy"
Sponsors
Beijing Friendship Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patient was diagnosed with benign pyloric and duodenal obstruction by gastroscopy, histopathological biopsy, abdominal plain CT, and upper gastrointestinal angiography; 2. Aged 18 to 80 years(including 18 and 80 years old); 3. Physical strength score: ECOG=70g/L; GR>=1.5x10^9/L; ALT and AST=75x10^9 /L; ALB>=30g/L, etc.); 6. Be able to understand and abide by the research protocol, agree and sign the informed consent; 7. Case data and follow-up data are relatively complete.
Exclusion criteria
Exclusion criteria: 1. Gastroscopy is contraindicated; 2. Patients who cannot tolerate anesthesia or surgery or refuse surgery; 3. Patients with coagulation dysfunction, cardiopulmonary insufficiency and other surgical contraindications, or those with a history of uncontrolled epilepsy, central nervous system disease or mental disorder, or those who require immunosuppressive therapy for organ transplantation; 4. Pathological diagnosis of malignant pyloric and duodenal obstruction; 5. During pregnancy and lactation, those who may not take effective contraceptive measures during pregnancy and those who are planning to conceive; 6. Patients with a history of digestive system tumors or abdominal surgery; 7. Participate in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of delayed gastric emptying within 30 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications within 30 days after surgery;Operation information (operation time, intraoperative blood loss);Postoperative gastrointestinal function recovery time;Recurrence rate after 3 years;Serum gastrin level;Pepsinogen levels;Gastric acid determination;13C breath test;Quality of life score;Drainage;Postoperative hospital stay;Hospital costs;Mortality within 30 days after surgery; | — |
Countries
China
Contacts
Public ContactZhang Jun
Beijing Friendship Hospital Affiliated to Capital Medical University
Outcome results
None listed