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Study on the clinical diagnostic value of dyscrasia caused by exosomal miRNA derived from gastric cancer cells

Study on the clinical diagnostic value of dyscrasia caused by exosomal miRNA derived from gastric cancer cells

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052195
Enrollment
Unknown
Registered
2021-10-22
Start date
2021-11-30
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stomach cancer

Interventions

Gold Standard:1. Weight loss >5% in the past 6 months
2. BMI 2%
3. Anthropometric measurement of muscle area in the middle of the upper arm (male <32 cm2, female <18 cm2)
4. Skeletal muscle index of limbs (male <7.26 kg/m2
female <5.45 kg/m2)
5. CT imaging lumbar&
Index test:The&#32
of&#32
in&#32
peripheral&#32
blood&#32
exosomes,&#32
has-miR-431-5p,&#32
has-miR-379-5p,&#32
has-miR-4433b-5p,&#32
has-miR-432-5p,&#32
has-miR-3138,&#32

Sponsors

The First Affiliated Hospital of the Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with gastric cancer diagnosed by tissue or cytopathology, 2. Have complete clinical and pathological data, 3. Aged over 18 years old.

Exclusion criteria

Exclusion criteria: 1. Combined with other tumors, chronic wasting diseases, metabolic diseases or other malignant diseases; 2. Non-tumor cachexia in the past; 3. Accompanied by hepatitis B virus, HIV virus and acute infection.

Design outcomes

Primary

MeasureTime frame
miRNA;

Countries

China

Contacts

Public ContactJiang Xunliang

The First Affiliated Hospital of the Air Force Medical University

jiangxunliang@fmmu.edu.cn+86 15120086148

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026