motoric cognitive risk syndrome
Conditions
Interventions
MCR stride length, MCRsl:None
MCR swing time, MCRsw:No
MCR stride length variability, MCRslv:None
MCR swing time variability, MCRswv:None
Sponsors
Jing'an District Centre Hospital of Shanghai, Fudan University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years old, take care of daily life, can cooperate to complete all functional assessments, and voluntarily sign the informed consent; 2. SCD was assessed using the consortium to establish a registry for Alzheimer's Disease (CERAD) questionnaire; the question was derived from an entry in the GDS-15. By asking the patient "Do you think you have more memory problems than others", if the answer is "yes", it means that the patient has subjective cognitive decline; 3. The pace is 1 standard deviation lower than the average pace of people of the same age and gender.
Exclusion criteria
Exclusion criteria: 1. Clinical diagnosis of dementia, mild cognitive impairment; 2. Clinical diagnosis of Parkinson's disease; 3. Movement disorders; 4. Incomplete or missing clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment, MoCA;Non-cognitive domain subtests;walking trail making test;Timed stand up and walk test;Three dimensional gait analysis parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination;Geriatric Depression Scale15-item, GDS- 15;Clinical fragile scale, CFS;short Falls Efficacy Scale International;fall risk assessment, FRA;Berg balance scale;Elderly questionnaires;body composition tests;grip strength;The Pittsburgh Sleep Quality Index, PSQI;Epworth Sleepiness Scale, ESS;Regions of interest activated voxel value;Lateralization indices, LI;Fractional anisotropy, FA;Functional links in brain regions; | — |
Countries
China
Contacts
Public ContactWang Bei
Jing'an District Centre Hospital of Shanghai, Fudan University
Outcome results
None listed