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The effects of acute normovolaemic haemodilution in patients with orthopaedic surgery

The effects of acute normovolaemic haemodilution on clotting function and inflammatory factors in patients with spinal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052154
Enrollment
Unknown
Registered
2021-10-20
Start date
2021-10-18
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal surgery

Interventions

Crystal group:2-3 times crystal dilution
Colloidal group:Equivalent hydroxyethyl dilution
Control group:No ANH

Sponsors

Gannan Medical University First Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with elective orthopedic spine surgery; 2. ASA I ~ II level.

Exclusion criteria

Exclusion criteria: 1. Hematocrit is less than 0.35; 2. Hemoglobin is less than 110 g/L; 3. Preoperative coagulation dysfunction; 4. Hypoproteinemia; 5. Patients with severe poor heart, lung, liver and kidney function.

Design outcomes

Primary

MeasureTime frame
TEG;IL-6, TNF-a, C reactive protein;—

Secondary

MeasureTime frame
Arterial blood gas analysis;—

Countries

China

Contacts

Public ContactXie Haiyu

Gannan Medical University

1543128504@qq.com+86 18379841309

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026