NODDI imaging differences of brain structures before and after carotid endarterectomy
Conditions
Interventions
Case series:No
Sponsors
Department of Jilin University, First Clinical Hospital of Bethune Medical
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Moderate or severe carotid stenosis (symptomatic carotid stenosis with stenosis >=50% and asymptomatic carotid stenosis with stenosis >=70%) diagnosed by head and neck CTA angiography; 2. Meet the indications for surgery, voluntarily choose to undergo carotid endarterectomy and sign the informed consent form for surgery; and there are no contraindications to surgery; 3. Have complete information on MRI before and after surgery (within 3 days) and 3 months after surgery.
Exclusion criteria
Exclusion criteria: 1. Contraindications for MRI examination; 2. Severe cardiopulmonary insufficiency, unable to perform carotid endarterectomy, or family members and patients choose carotid artery stent implantation; 3. There is a severe systemic genetic or acquired disease in the past medical history (especially severe mental/neurological disease and/or severe stroke); 4. Patients who failed to undergo postoperative follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| orientation dispersion index;intracellular volume fraction;volume fraction of the istropiccompartment; | — |
Countries
China
Contacts
Public ContactXu Baofeng
Department of Jilin University, First Clinical Hospital of Bethune Medical
Outcome results
None listed