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Study on the difference of intestinal flora between patients with perianal abscess before and after operation and healthy people

Based on 16S rDNA sequence analysis of the difference of intestinal flora between patients with perianal abscess before and after surgery and healthy people

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052142
Enrollment
Unknown
Registered
2021-10-20
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perianal abscess

Interventions

Observation group:No
Control group:No

Sponsors

Jiaxing Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years; 2. Meet the diagnostic criteria for perianal abscess; 3. The defecation function was normal before the operation, and the defecation was smooth; 4. Agree to perform perianal abscess incision and drainage; 5. Sign the informed consent; 6. Live in the area for more than half a year, and deny bad habits such as smoking and drinking.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic constipation or diarrhea; 2. Patients with inflammatory bowel disease and intestinal tuberculosis; 3. Patients with colorectal tumor; 4. Other diseases that may affect the intestinal flora: other acute and chronic intestinal diseases, such as functional bowel disease (irritable bowel syndrome, etc.), non-infectious diarrhea; and cardiovascular and cerebrovascular diseases, diabetes, chronic liver disease, acute Chronic nephritis and upper gastrointestinal diseases such as peptic ulcer; 5. Combined with abnormal coagulation function or current anticoagulation therapy; 6. Patients who are pregnant or breastfeeding; 7. Intellectual disability or a history of mental illness; 8. Those who have taken antibiotics, probiotics and other drugs that obviously affect the intestinal flora 4 weeks before the selection; 9. Those with poor compliance and unable to complete the follow-up.

Design outcomes

Primary

MeasureTime frame
Fecal 16s rDNA diversity sequencing;

Countries

China

Contacts

Public ContactYin Hezhai

Jiaxing Hospital of Traditional Chinese Medicine

yhz51560@163.com+86 13736854239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026