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Repetitive transcranial magnetic (rTMS) combined with transcranial direct current (tDCS) stimulation to treat and improve cognitive function depression:Clinical randomized controlled study

Repetitive transcranial magnetic (rTMS) combined with transcranial direct current (tDCS) stimulation to treat and improve cognitive function depression:Clinical randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052122
Enrollment
Unknown
Registered
2021-10-19
Start date
2021-10-18
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Experimental group1:real tDCS, real rTMS
Experimental group2:real tDCS, sham rTMS
Experimental group3:real rTMS, sham tDCS
Control group:sham rTMS, sham tDCS

Sponsors

Ningbo Kangning Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for depression in the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (International Classification of Diseases, ICD-10); 2. Aged 18 to 65 years; 3. Right-handed; 4. The Ethics Committee of the Municipal Psychiatric Hospital agreed, and the subjects signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe physical diseases, infectious diseases and immune system diseases; 2. Patients with severe neurological disease, mental retardation or organic brain disease; 3. Pregnant or lactating women; 4. Those who received electroconvulsive therapy within the past 3 months; 5. Have a history of epileptic seizures; 6. Those who are not suitable to receive rTMS or tDCS treatment after evaluation, and those who cannot complete the collection of relevant indicators.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale score;Hamilton Anxiety Scale Score;Reproducible neuropsychological state measure scores;Toronto Alexithymia Scale;Transcranial Magnetic Stimulation Combined with EMG Monitoring System;Near infrared functional imaging system;

Countries

China

Contacts

Public ContactZhou Dongsheng

Ningbo Kangning Hospital

wyzhouds@sina.com+86 574 26302520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 3, 2026